Sickle Cell Disease affects millions of people around the world—90% being people of color—but the disease remains widely overlooked and often invisible. With a lack of awareness leading to underfunding for research and treatment, societal stigma, and disparities in care. The blood disorder causes healthy round blood cells to become abnormally crescent shaped and get stuck in blood vessels—leading to life-threatening complications. To make Sickle Cell Disease visible to the world, we created the Sickle Cell Ball—a basketball with a single red crescent. Created by the Dalio Center of Health Justice at NewYork-Presbyterian in partnership with the NBA and their official ball sponsor, Wilson. The Sickle Cell Ball launched during Sickle Cell Awareness month and immediately put the disease in the global spotlight. Thousands of Sickle Cell Balls were designed, produced, and passed to patients, doctors, hospitals, the NCAA, the NBA, the NFL, and ESPN hosts. It got featured in trick shot challenges, basketball tournaments, and even in the most popular basketball video game in the world—NBA 2K25—allowing millions of gamers to learn about Sickle Cell Disease. Raising much needed awareness and funding for clinical programs. Helping research teams continue to pioneer potential new treatments and making Sickle Cell disease impossible to ignore.