CONTEXT In Europe, it is estimated that 20% to 40% of adults are at high or very high cardiovascular risk. Cardiovascular disease remains the leading cause of death in the region, accounting for over 3.9 million deaths annually. Cholesterol is one of the primary contributors. Yet, society remains largely unaware of the dangers posed by clogged arteries caused by high cholesterol levels. IDEA We wanted to demonstrate how high cholesterol levels can lead to heart failure by clogging the arteries. To illustrate this, we brought cholesterol to the streets—right into the heart of various European cities—clogging their main arteries. We narrowed the alleys, interrupted traffic, and symbolically blocked city life using 10 people inside large balls representing cholesterol.